Semimechanistic pharmacokinetic and pharmacodynamic modeling of piperaquine in a volunteer infection study with plasmodium falciparum blood-stage Malaria
Dihydroartemisinin-piperaquine is a recommended first-line artemisinin combination therapy for Plasmodium falciparum malaria. Piperaquine is also under consideration for other antimalarial combination therapies. The aim of this study was to develop a pharmacokinetic-pharmacodynamic model that might...
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Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Published: |
2022
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/78312 |
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Institution: | Mahidol University |