Semimechanistic pharmacokinetic and pharmacodynamic modeling of piperaquine in a volunteer infection study with plasmodium falciparum blood-stage Malaria

Dihydroartemisinin-piperaquine is a recommended first-line artemisinin combination therapy for Plasmodium falciparum malaria. Piperaquine is also under consideration for other antimalarial combination therapies. The aim of this study was to develop a pharmacokinetic-pharmacodynamic model that might...

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Bibliographic Details
Main Authors: Thanaporn Wattanakul, Mark Baker, Joerg Mohrle, Brett McWhinney, Richard M. Hoglund, James S. McCarthy, Joel Tarning
Other Authors: Faculty of Tropical Medicine, Mahidol University
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/78312
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Institution: Mahidol University

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