Semimechanistic pharmacokinetic and pharmacodynamic modeling of piperaquine in a volunteer infection study with plasmodium falciparum blood-stage Malaria
Dihydroartemisinin-piperaquine is a recommended first-line artemisinin combination therapy for Plasmodium falciparum malaria. Piperaquine is also under consideration for other antimalarial combination therapies. The aim of this study was to develop a pharmacokinetic-pharmacodynamic model that might...
Saved in:
Main Authors: | Thanaporn Wattanakul, Mark Baker, Joerg Mohrle, Brett McWhinney, Richard M. Hoglund, James S. McCarthy, Joel Tarning |
---|---|
Other Authors: | Faculty of Tropical Medicine, Mahidol University |
Format: | Article |
Published: |
2022
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/78312 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
Similar Items
-
Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria
by: J. Tarning, et al.
Published: (2018) -
Population pharmacokinetics and antimalarial pharmacodynamics of piperaquine in patients with Plasmodium vivax Malaria in Thailand
by: J. Tarning, et al.
Published: (2018) -
Optimizing dihydroartemisinin-piperaquine dose regimens in a paediatric population: a pharmacokinetic-pharmacodynamic approach using monte-carlo simulations
by: Palang Chotsiri, et al.
Published: (2015) -
Pharmacokinetics of piperaquine in pregnant women in Sudan with uncomplicated Plasmodium falciparum malaria
by: Ishag Adam, et al.
Published: (2018) -
Pharmacokinetics of dihydroartemisinin and piperaquine in pregnant and nonpregnant women with uncomplicated falciparum malaria
by: Marcus J. Rijken, et al.
Published: (2018)