Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria.

• Main Authors: White, Nicholas J, Ashley, Elizabeth A, Recht, Judith, Delves, Michael J, Ruecker, Andrea, Smithuis, Frank M, Eziefula, Alice C, Bousema, Teun, Drakeley, Chris, Kesinee Chotivanich, เกศินี โชติวานิช, Mallika Imwong, มัลลิกา อิ่มวงศ์, Sasithon Pukrittayakamee, ศศิธร ผู้กฤตยาคามี, Jetsumon Prachumsri, เจตสุมน ประจำศรี, Chu, Cindy, Andolina, Chiara, Bancone, Germana, Hien, Tran T, Mayxay, Mayfong, Taylor, Walter RJ, Seidlein, Lorenz von, Price, Ric N, Barnes, Karen I, Djimdé, Abdoulaye, ter Kuile, Feiko, Gosling, Roly, Chen, Ingrid, Dhorda, Mehul J, Stepniewska, Kasia, Guérin, Philippe, Woodrow, Charles J, Dondorp, Arjen M, Day, Nicholas PJ, Nosten, Francois H
• Format: Article
• Language: English
• Published: 2015
• Subjects: Drugs; Gametocytocidal; Malaria; Plasmodium falciparum; Therapeutic; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/843
• Institution: Mahidol University

Indirect clinical measures assessing anti-malarial drug transmission-blocking activity in falciparum malaria include measurement of the duration of gametocytaemia, the rate of gametocyte clearance or the area under the gametocytaemia-time curve (AUC). These may provide useful comparative informa...