3, 4-diaminopyridine reverses respiratory paralysis induced by a presynaptically active snake venom and its major neurotoxin

3, 4-diaminopyridine reverses respiratory paralysis induced by a presynaptically active snake venom and its major neurotoxin

Presynaptically active snake venom neurotoxins induce a potentially fatal neuromuscular blockade which cannotbe reliably overcome by current therapy. The drug 3, 4-diaminopyridine (DAP) is effective in other presynaptic paralytic conditions and was therefore tried in anaesthetized rabbits with respi...

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Bibliographic Details
Main Authors: George Watt, C. D. Smith, A. Kaewsupo, T. M.E. Davis
Other Authors: Armed Forces Research Institute of Medical Sciences, Thailand
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/9600
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/9600

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