3, 4-diaminopyridine reverses respiratory paralysis induced by a presynaptically active snake venom and its major neurotoxin
Presynaptically active snake venom neurotoxins induce a potentially fatal neuromuscular blockade which cannotbe reliably overcome by current therapy. The drug 3, 4-diaminopyridine (DAP) is effective in other presynaptic paralytic conditions and was therefore tried in anaesthetized rabbits with respi...
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Main Authors: | George Watt, C. D. Smith, A. Kaewsupo, T. M.E. Davis |
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Other Authors: | Armed Forces Research Institute of Medical Sciences, Thailand |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/9600 |
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Institution: | Mahidol University |
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