Therapy insight: Heart disease and the insulin-resistant patient

by Cook S.A., Aitman T., Naoumova R.P.
Published 2018

Genetics of coronary heart disease

by Naoumova R., Cook S.A., Cook P., Aitman T.J.
Published 2018

Reply: Normalization procedures and detection of linkage signal in genetical-genomics experiments [6]

by Petretto E., Mangion J., Cook S.A., Aitman T.J., Pravenec M., Schulz H., Fischer J., Hubner N.
Published 2018

Genome-wide co-expression analysis in multiple tissues

by Grieve I.C., Dickens N.J., Pravenec M., Kren V., Hubner N., Cook S.A., Aitman T.J., Petretto E., Mangion J.
Published 2018

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

by Langley S.R., Bottolo L., Kunes J., Zicha J., Zidek V., Hubner N., Cook S.A., Pravenec M., Aitman T.J., Petretto E.
Published 2018

Genetic loci modulate macrophage activity and glomerular damage in experimental glomerulonephritis

by Jacques Behmoaras, Jennifer Smith, Zelpha D'Souza, Gurjeet Bhangal, Ratana Chawanasuntoropoj, Frederick W.K. Tam, Charles D. Pusey, Timothy J. Aitman, H. Terence Cook
Published 2018

Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1? synthesis in macrophages

by Hull R.P., Srivastava P.K., D'Souza Z., Atanur S.S., Mechta-Grigoriou F., Game L., Petretto E., Cook H.T., Aitman T.J., Behmoaras J.
Published 2018

Distribution and functional impact of DNA copy number variation in the rat

by Guryev V., Saar K., Adamovic T., Verheul M., Van Heesch S.A.A.C., Cook S., Pravenec M., Aitman T., Jacob H., Shull J.D., Hubner N., Cuppen E.
Published 2018

New insights into the genetic control of gene expression using a bayesian multi-tissue approach

by Petretto E., Bottolo L., Langley S.R., Heinig M., McDermott-Roe C., Sarwar R., Pravenec M., Hübner N., Aitman T.J., Cook S.A., Richardson S.
Published 2018

Heritability and tissue specificity of expression quantitative trait loci

by Petretto E., Mangion J., Dickens N.J., Cook S.A., Kumaran M.K., Lu H., Fischer J., Maatz H., Kren V., Pravenec M., Hubner N., Aitman T.J.
Published 2018

Identification of ceruloplasmin as a gene that affects susceptibility to glomerulonephritis through macrophage function

by Chen, T.-D, Rotival, M, Chiu, L.-Y, Bagnati, M, Ko, J.-H, Srivastava, P.K, Petretto, E, Pusey, C.D, Lai, P.-C, Aitman, T.J, Cook, H.T, Behmoaras, J
Published 2020

DNA Methylation Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononu...

by Wong, C.L., Ma, B., Adamowicz-Brice, M., Gerrard, G., Norziha, Z.A., Tumian, N.R., Cheong, S.K., Leong, C.F., Bee, P.C., Gan, G.G., Sathar, J., Foroni, L., Aitman, T., Liang, L., Laffan, M.
Published 2015

Targeted Sequencing of Sorted Peripheral Blood Cells Reveals Novel Germline and Somatic Variants in the Polymorphonuclear and Mononuclear Cells of Patients with Essential Thrombocy...

by Wong, C.L., Gerrard, G., Adamowicz-Brice, M., Norziha, Z.A., Tumian, N.R., Cheong, S.K., Leong, C.F., Bee, P.C., Gan, G.G., Sathar, J., Ma, B., Liang, L., Aitman, T., Foroni, L., Laffan, M.
Published 2015

Gene Expression Profiling of Sorted Peripheral Blood Cells Using Microarray and Next Generation Sequencing Reveals Distinct Molecular Signatures in the Polymorphonuclear and Mononu...

by Wong, C.L., Ma, B., Gerrard, G., Adamowicz-Brice, M., Norziha, Z.A., Tumian, N.R., Cheong, S.K., Leong, C.F., Bee, P.C., Gan, G.G., Sathar, J., Lye, S.F., Foroni, L., Aitman, T., Liang, L., Laffan, M.
Published 2015

Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis

by Olona, A., Terra, X., Ko, J.-H., Grau-Bové, C., Pinent, M., Ardevol, A., Diaz, A.G., Moreno-Moral, A., Edin, M., Bishop-Bailey, D., Zeldin, D.C., Aitman, T.J., Petretto, E., Blay, M., Behmoaras, J.
Published 2021

Genetic Analysis of the Cardiac Methylome at Single Nucleotide Resolution in a Model of Human Cardiovascular Disease

by Johnson M.D., Mueller M., Adamowicz-Brice M., Collins M.J., Gellert P., Maratou K., Srivastava P.K., Rotival M., Butt S., Game L., Atanur S.S., Silver N., Norsworthy P.J., Langley S.R., Petretto E., Pravenec M., Aitman T.J.
Published 2018

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease

by Hubner N., Wallace C.A., Zimdahl H., Petretto E., Schulz H., Maciver F., Mueller M., Hummel O., Monti J., Zidek V., Musilova A., Kren V., Causton H., Game L., Born G., Schmidt S., M�ller A., Cook S.A., Kurtz T.W., Whittaker J., Pravenec M., Aitman T.J.
Published 2018

Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass

by Petretto E., Sarwar R., Grieve I., Lu H., Kumaran M.K., Muckett P.J., Mangion J., Schroen B., Benson M., Punjabi P.P., Prasad S.K., Pennell D.J., Kiesewetter C., Tasheva E.S., Corpuz L.M., Webb M.D., Conrad G.W., Kurtz T.W., Kren V., Fischer J., Hubner N., Pinto Y.M., Pravenec M., Aitman T.J., Cook S.A.
Published 2018

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

by Heinig M., Petretto E., Wallace C., Bottolo L., Rotival M., Lu H., Li Y., Sarwar R., Langley S.R., Bauerfeind A., Hummel O., Lee Y.-A., Paskas S., Rintisch C., Saar K., Cooper J., Buchan R., Gray E.E., Cyster J.G., Jeanette Erdmann, Hengstenberg C., Maouche S., Ouwehand W.H., Rice C.M., Samani N.J., Schunkert H., Goodall A.H., Schulz H., Roider H.G., Vingron M., Blankenberg S., M�nzel T., Zeller T., Szymczak S., Ziegler A., Tiret L., Smyth D.J., Pravenec M., Aitman T.J., Cambien F., Clayton D., Todd J.A., Hubner N., Cook S.A., Braund P., Gracey J., Krishnan U., Moore J.S., Nelson C.P., Pollard H., Attwood T., Crisp-Hihn A., Foad N., Jolley J., Lloyd-Jones H., Muir D., Murray E., O'Leary K., Rankin A., Sambrook J., Godfroy T., Brocheton J., Proust C., Schmitz G., Heimerl S., Lugauer I., Belz S., Gulde S., Linsel-Nitschke P., Sager H., Schroeder L., Lundmark P., Syvannen A.-C., Neudert J., Scholz M., Deloukas P., Gray E., Gwilliams R., Niblett D.
Published 2018