H3K27ME3-RICH GENOMIC REGIONS CAN FUNCTION AS SILENCERS TO REPRESS GENE EXPRESSION VIA CHROMATIN INTERACTIONS

by CAI YICHAO
Published 2020

Chromatin loop anchors can predict transcript and exon usage

by Zhang, Yu, Cai, Yichao, Francesc Xavier, Roca Castella, Chee, Keong Kwoh, Fullwood, Melissa Jane
Published 2023

Exploring the roles for repressive and quiescent chromatin regions in 3D organization of the human genome

by Cai, Yichao, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Babu, Deepak, An, Omer, Yang, Henry, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published 2019

Chromatin interaction neural network (ChINN) : a machine learning-based method for predicting chromatin interactions from DNA sequences

by Cao, Fan, Zhang, Yu, Cai, Yichao, Animesh, Sambhavi, Zhang, Ying, Akincilar, Semih Can, Loh, Yan Ping, Li, Xinya, Chng, Wee Joo, Tergaonkar, Vinay, Kwoh, Chee Keong, Fullwood, Melissa Jane
Published 2021

Chromatin interaction neural network (ChINN): a machine learning-based method for predicting chromatin interactions from DNA sequences

by Cao, Fan, Zhang, Yu, Cai, Yichao, Animesh, Sambhavi, Zhang, Ying, Akincilar, Semih Can, Loh, Yan Ping, Li, Xinya, Chng, Wee Joo, Tergaonkar, Vinay, Kwoh, Chee Keong, Fullwood, Melissa J
Published 2021

H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions

by Cai, Yichao, Zhang, Ying, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Cao, Zhendong, Raju, Anandhkumar, Lieberman Aiden, Erez, Li, Shang, Manikandan, Lakshmanan, Tergaonkar, Vinay, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published 2021

H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions

by Cai, Yichao, Zhang, Ying, Loh, Yan Ping, Tng, Jia Qi, Lim, Mei Chee, Cao, Zhendong, Raju, Anandhkumar, Lieberman Aiden, Erez, Li, Shang, Manikandan, Lakshmanan, Tergaonkar, Vinay, Tucker-Kellogg, Greg, Fullwood, Melissa Jane
Published 2022

Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth

by Zhang, Ying, Chen, Kaijing, Tang, Seng Chuan, Cai, Yichao, Nambu, Akiko, See, Yi Xiang, Fu, Chaoyu, Raju, Anandhkumar, Lebeau, Benjamin, Ling, Zixun, Chan, Jia Jia, Tay, Yvonne, Mutwil, Marek, Lakshmanan, Manikandan, Tucker-Kellogg, Greg, Chng, Wee Joo, Tenen, Daniel G, Osato, Motomi, Tergaonkar, Vinay, Fullwood, Melissa Jane
Published 2024