IDENTIFY FUNCTIONAL PROTEINS INTERACTING WITH MMSET IN MULTIPLE MYELOMA

by CHOOI JING YUAN
Published 2018

SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic PTP4A3 through Chromatin Remodeling in t(4;14) Multiple Myeloma

by Chong, Phyllis SY, Chooi, Jing Yuan, Lim, Julia SL, Toh, Sabrina Hui Min, Tan, Tuan Zea, Chng, Wee-Joo
Published 2021

NF-kappa B promotes the stem-like properties of leukemia cells by activation of LIN28B

by Zhou, Jianbiao, Chooi, Jing-Yuan, Ching, Ying Qing, Quah, Jessie Yiying, Toh, Sabrina Hui-Min, Ng, Yvonne, Tan, Tuan Zea, Chng, Wee-Joo
Published 2022

Non-canonical activation of beta-catenin by PRL-3 phosphatase in acute myeloid leukemia

by Chong, Phyllis SY, Zhou, Jianbiao, Chooi, Jing-Yuan, Chan, Zit-Liang, Toh, Sabrina Hui Min, Tan, Tuan Zea, Wee, Sheena, Gunaratne, Jayantha, Zeng, Qi, Chng, Wee-Joo
Published 2020

IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple Myeloma

by Chong, Phyllis SY, Zhou, Jianbiao, Lim, Julia SL, Hee, Yan Ting, Chooi, Jing-Yuan, Chung, Tae-Hoon, Tan, Zea Tuan, Zeng, Qi, Waller, Daniel D, Sebag, Michael, Chng, Wee-Joo
Published 2020

ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.

by Zhou, Jianbiao, Yiying Quah, Jessie, Ng, Yvonne, Chooi, Jing-Yuan, Hui-Min Toh, Sabrina, Lin, Baohong, Zea Tan, Tuan, Hosoi, Hiroki, Osato, Motomi, Seet, Qihui, Ooi, Lisa AG, Lindmark, Bertil, McHale, Mark, Chng, Wee-Joo
Published 2022

Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore

by Pratanwanich, Ploy N, Yao, Fei, Chen, Ying, Koh, Casslynn WQ, Wan, Yuk Kei, Hendra, Christopher, Poon, Polly, Goh, Yeek Teck, Yap, Phoebe ML, Chooi, Jing Yuan, Chng, Wee Joo, Ng, Sarah B, Thiery, Alexandre, Goh, WS Sho, Goke, Jonathan
Published 2021

Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis

by Teoh, Phaik Ju, An, Omer, Chung, Tae-Hoon, Chooi, Jing Yuan, Toh, Sabrina HM, Fan, Shuangyi, Wang, Wilson, Koh, Bryan TH, Fullwood, Melissa J, Ooi, Melissa G, de Mel, Sanjay, Soekojo, Cinnie Y, Chen, Leilei, Ng, Siok Bian, Yang, Henry, Chng, Wee Joo
Published 2019

Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa J, Xiong, Sinan, Toh, Sabrina HM, Balan, Kalpnaa, Wong, Regina WJ, Lim, Julia SL, Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Published 2023

Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma

by Mustafa, Nurulhuda, Nee, Adina Huey Fang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Chung, Tae-Hoon, Selvarajan, Viknesvaran, Fan, Shuangyi, Ng, Siok Bian, Poon, Michelle, Chan, Esther, Lee, Joanne, Chee, Yen Lin, Jeyasekharan, Anand D, Zhou, Longen, Yang, Jennifer, Chng, Wee Joo
Published 2021

Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Wong, Regina Wan Ju, Chooi, Jing-Yuan, Lim, Julia Sze Lynn, Sanda, Takaomi, Ooi, Melissa, De Mel, Sanjay, Soekojo, Cinnie, Chen, Yongxia, Zhang, Enfan, Cai, Zhen, Shen, Peng, Ruan, Jian, Chng, Wee-Joo
Published 2021

Super enhancer-mediated upregulation of HJURP promotes growth and survival of t(4;14)-positive multiple myeloma

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa Jane, Xiong, Sinan, Toh, Sabrina H. M., Balan, Kalpnaa, Wong, Regina W. J., Lim, Julia S. L., Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Published 2022

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML

by Zhou, Jianbiao, Chan, Zit-Liang, Bi, Chonglei, Lu, Xiao, Chong, Phyllis SY, Chooi, Jing-Yuan, Cheong, Lip-Lee, Liu, Shaw-Cheng, Ching, Ying Qing, Zhou, Yafeng, Osato, Motomi, Tan, Tuan Zea, Ng, Chin Hin, Ng, Siok-Bian, Wang, Shi, Zeng, Qi, Chng, Wee-Joo
Published 2021