Liposomal Systems as Nanocarriers for the Antiviral Agent Ivermectin

by Croci, R, Bottaro, E, Chan, K.W.K, Watanabe, S, Pezzullo, M, Mastrangelo, E, Nastruzzi, C
Published 2020

The Potential Role of the ZIKV NS5 Nuclear Spherical-Shell Structures in Cell Type-Specific Host Immune Modulation during ZIKV Infection

by Tan, M.J.A., Chan, K.W.K., Ng, I.H.W., Kong, S.Y.Z., Gwee, C.P., Watanabe, S., Vasudevan, S.G.
Published 2021

Flexibility of NS5 methyltransferase-polymerase linker region is essential for dengue virus replication

by Zhao Y., Soh T.S., Chan K.W.K., Fung S.S.Y., Swaminathan K., Lim S.P., Shi P.-Y., Huber T., Lescar J., Luo D., Vasudevan S.G.
Published 2020

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production

by Tay M.Y.F., Smith K., Ng I.H.W., Chan K.W.K., Zhao Y., Ooi E.E., Lescar J., Luo D., Jans D.A., Forwood J.K., Vasudevan S.G.
Published 2018

Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag- CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assa...

by Loh C.C.Y., Suwanarusk R., Lee Y.Q., Chan K.W.K., Choy K.-Y., Rénia L., Russell B., Lear M.J., Nosten F.H., Tan K.S.W., Chow L.M.C.
Published 2018

A Non-structural 1 Protein G53D Substitution Attenuates a Clinically Tested Live Dengue Vaccine

by Choy, M.M., Ng, D.H.L., Siriphanitchakorn, T., Ng, W.C., Sundstrom, K.B., Tan, H.C., Zhang, S.L., Chan, K.W.K., Manuel, M., Kini, R.M., Chan, K.R., Vasudevan, S.G., Ooi, E.E.
Published 2021

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

by Zhao Y., Soh T.S., Zheng J., Chan K.W.K., Phoo W.W., Lee C.C., Tay M.Y.F., Swaminathan K., Cornvik T.C., Lim S.P., Shi P.-Y., Lescar J., Vasudevan S.G., Luo D.
Published 2018

A systematic approach to the development of a safe live attenuated Zika vaccine

by Kwek, S.S, Watanabe, S, Chan, K.R, Ong, E.Z, Tan, H.C, Ng, W.C, Nguyen, M.T.X, Gan, E.S, Zhang, S.L, Chan, K.W.K, Tan, J.H, Sessions, O.M, Manuel, M, Pompon, J, Chua, C, Hazirah, S, Tryggvason, K, Vasudevan, S.G, Ooi, E.E
Published 2020

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

by Sung C., Wei Y., Watanabe S., Lee H.S., Khoo Y.M., Fan L., Rathore A.P.S., Chan K.W.-K., Choy M.M., Kamaraj U.S., Sessions O.M., Aw P., de Sessions P.F., Lee B., Connolly J.E., Hibberd M.L., Vijaykrishna D., Wijaya L., Ooi E.E., Low J.G.-H., Vasudevan S.G.
Published 2018