Targeting cell signaling and apoptotic pathways by dietary agents: Role in the prevention and treatment of cancer

by Shanmugam, M.K., Kannaiyan, R., Sethi, G.
Published 2014

Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer

by Kannaiyan, R., Shanmugam, M.K., Sethi, G.
Published 2014

Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of multiple myeloma

by Sikka, S., Shanmugam, M.K., Kannaiyan, R., Surana, R., Shin, E.M., Kumar, A.P., Sethi, G., Ahn, K.S.
Published 2014

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-?B regulated gene products in multiple myeloma xenograft mouse mod...

by Siveen, K.S, Mustafa, N, Li, F, Kannaiyan, R, Ahn, K.S, Kumar, A.P, Chng, W.-J, Sethi, G
Published 2020

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways

by Kannaiyan, R., Manu, K.A., Chen, L., Li, F., Rajendran, P., Subramaniam, A., Lam, P., Kumar, A.P., Sethi, G.
Published 2014

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells

by Kannaiyan, R., Hay, H.S., Rajendran, P., Li, F., Shanmugam, M.K., Vali, S., Abbasi, T., Kapoor, S., Sharma, A., Kumar, A.P., Chng, W.-J., Sethi, G.
Published 2014

Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myeloma

by Shanmugam, M.K, Ahn, K.S, Lee, J.H, Kannaiyan, R, Mustafa, N, Manu, K.A, Siveen, K.S, Sethi, G, Chng, W.J, Kumar, A.P
Published 2020

Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade In Vitro and In Vivo

by Rajendran, P., Li, F., Shanmugam, M.K., Kannaiyan, R., Goh, J., Wong, K., Wang, W., Khin, E., Tergaonkar, V., Kumar, A., Luk, J.M., Sethi, G.
Published 2014

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

by Manu, K.A., Shanmugam, M.K., Rajendran, P., Li, F., Ramachandran, L., Hay, H.S., Kannaiyan, R., Swamy, S.N., Vali, S., Kapoor, S., Ramesh, B., Bist, P., Koay, E.S., Lim, L.H.K., Ahn, K.S., Kumar, A.P., Sethi, G.
Published 2014