Dengue virus non-structural protein 5

بواسطة Sahili, A.E, Lescar, J
منشور في 2020

Substrate Channel Flexibility in Pseudomonas aeruginosa MurB Accommodates Two Distinct Substrates

بواسطة Chen M.W., Lohkamp B., Schnell R., Lescar J., Schneider G.
منشور في 2020

Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein

بواسطة Chu, JJH, Rajamanonmani, R, Li, J, Bhuvanakantham, R, Lescar, J, Ng, ML
منشور في 2020

Structure of a diguanylate cyclase from thermotoga maritima: Insights into activation, feedback inhibition and thermostability

بواسطة Deepthi A., Liew C.W., Liang Z.-X., Swaminathan K., Lescar J.
منشور في 2018

Crystallographic structure of ubiquitin in complex with cadmium ions

بواسطة Qureshi, I.A, Ferron, F, Seh, C.C, Cheung, P, Lescar, J
منشور في 2020

Towards the design of antiviral inhibitors against flaviviruses: The case for the multifunctional NS3 protein from Dengue virus as a target

بواسطة Lescar, J., Luo, D., Xu, T., Sampath, A., Lim, S.P., Canard, B., Vasudevan, S.G.
منشور في 2014

Rigidifying acyl carrier protein domain in iterative type i PKS CalE8 does not affect its function

بواسطة Lim, J., Sun, H., Fan, J.-S., Hameed, I.F., Lescar, J., Liang, Z.-X., Yang, D.
منشور في 2014

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody

بواسطة Wong, Y.H, Kumar, A, Liew, C.W, Tharakaraman, K, Srinivasaraghavan, K, Sasisekharan, R, Verma, C, Lescar, J
منشور في 2020

Crystal structure of the Dengue virus methyltransferase bound to a 5?-capped octameric RNA

بواسطة Yap L.J., Luo D., Chung K.Y., Lim S.P., Bodenreider C., Noble C., Shi P.-Y., Lescar J.
منشور في 2019

Functional evolution in orthologous cell-encoded RNA-dependent RNA polymerases

بواسطة Qian, X, Hamid, F.M, El Sahili, A, Darwis, D.A, Wong, Y.H, Bhushan, S, Makeyev, E.V, Lescar, J
منشور في 2020

The protein kinase CK2 catalytic domain from Plasmodium falciparum: Crystal structure, tyrosine kinase activity and inhibition

بواسطة Ruiz-Carrillo, D, Lin, J, El Sahili, A, Wei, M, Sze, S.K, Cheung, P.C.F, Doerig, C, Lescar, J
منشور في 2020

Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites

بواسطة Gao X., Yeo K.P., Aw S.S., Kuss C., Iyer J.K., Genesan S., Rajamanonmani R., Lescar J., Bozdech Z., Preiser P.R.
منشور في 2020

The hexamer structure of the Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes

بواسطة Ferron F., Li Z., Danek E.I., Luo D., Wong Y., Coutard B., Lantez V., Charrel R., Canard B., Walz T., Lescar J.
منشور في 2020

Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications

بواسطة Luo, D., Wei, N., Doan, D.N., Paradkar, P.N., Chong, Y., Davidson, A.D., Kotaka, M., Lescar, J., Vasudevan, S.G.
منشور في 2014

Mutagenesis of the dengue virus type 2 NS5 methyltransferase domain

بواسطة Kroschewski, H., Siew, P.L., Butcher, R.E., Thai, L.Y., Lescar, J., Wright, P.J., Vasudevan, S.G., Davidson, A.D.
منشور في 2014

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

بواسطة Phoo, W.W, Li, Y, Zhang, Z, Lee, M.Y, Loh, Y.R, Tan, Y.B, Ng, E.Y, Lescar, J, Kang, C, Luo, D
منشور في 2020

NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication.

بواسطة Swarbrick, C.M.D., CHANDRAKALA BASAVANNACHARYA, CHAN WING KI KITTI, CHAN SHU ANN, DALJIT SINGH, WEI NA, Phoo, W.W., Luo, D., Lescar, J., VASUDEVAN SUBHASH
منشور في 2020

Flexibility of NS5 methyltransferase-polymerase linker region is essential for dengue virus replication

بواسطة Zhao Y., Soh T.S., Chan K.W.K., Fung S.S.Y., Swaminathan K., Lim S.P., Shi P.-Y., Huber T., Lescar J., Luo D., Vasudevan S.G.
منشور في 2020

Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-o-methyltransferase nsp10/nsp16 complex

بواسطة Decroly E., Debarnot C., Ferron F., Bouvet M., Coutard B., Imbert I., Gluais L., Papageorgiou N., Sharff A., Bricogne G., Ortiz-Lombardia M., Lescar J., Canard B.
منشور في 2020

Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein

بواسطة Luo, D., Xu, T., Watson, R.P., Scherer-Becker, D., Sampath, A., Jahnke, W., Yeong, S.S., Wang, C.H., Lim, S.P., Strongin, A., Vasudevan, S.G., Lescar, J.
منشور في 2014