West Nile virus drug discovery

由 Lim, S.P, Shi, P.-Y
出版 2020

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

由 Poh, M.K., Shui, G., Xie, X., Shi, P.-Y., Wenk, M.R., Gu, F.
出版 2014

West nile virus experimental evolution in vivo and the trade-off hypothesis

由 Deardorff E.R., Fitzpatrick K.A., Jerzak G.V.S., Shi P.-Y., Kramer L.D., Ebel G.D.
出版 2019

Crystal structure of the Dengue virus methyltransferase bound to a 5?-capped octameric RNA

由 Yap L.J., Luo D., Chung K.Y., Lim S.P., Bodenreider C., Noble C., Shi P.-Y., Lescar J.
出版 2019

A Single Amino Acid Substitution in the Core Protein of West Nile Virus Increases Resistance to Acidotropic Compounds

由 Martín-Acebes M.A., Blázquez A.-B., de Oya N.J., Escribano-Romero E., Shi P.-Y., Saiz J.-C.
出版 2019

Evaluation of a novel reporter virus neutralization test for serological diagnosis of Zika and Dengue virus infection

由 Shan, C, Ortiz, D.A, Yang, Y, Wong, S.J, Kramer, L.D, Shi, P.-Y, Loeffelholz, M.J, Ren, P
出版 2020

The Interface between Methyltransferase and Polymerase of NS5 Is Essential for Flavivirus Replication

由 Li X.-D., Shan C., Deng C.-L., Ye H.-Q., Shi P.-Y., Yuan Z.-M., Gong P., Zhang B.
出版 2019

Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions

由 Whitehorn J., Yacoub S., Anders K.L., Macareo L.R., Cassetti M.C., Nguyen Van V.C., Shi P.-Y., Wills B., Simmons C.P.
出版 2019

Resistance analysis of an antibody that selectively inhibits dengue virus serotype-1

由 Zou, G., Kukkaro, P., Lok, S.-M., Ng, J.K.W., Tan, G.K., Hanson, B.J., Alonso, S., MacAry, P.A., Shi, P.-Y.
出版 2016

Therapeutics for Dengue: Recommendations for Design and Conduct of Early-Phase Clinical Trials

由 Simmons C.P., Wolbers M., Nguyen M.N., Whitehorn J., Shi P.Y., Young P., Petric R., Nguyen V.V.C., Farrar J., Wills B.
出版 2019

A small molecule fusion inhibitor of dengue virus

由 Poh, M.K., Yip, A., Zhang, S., Ma, N.L., Shi, P.-Y., Schul, W., Wenk, M.R., Smit, J.M., Wilschut, J., Priestle, J.P.
出版 2011

Flexibility of NS5 methyltransferase-polymerase linker region is essential for dengue virus replication

由 Zhao Y., Soh T.S., Chan K.W.K., Fung S.S.Y., Swaminathan K., Lim S.P., Shi P.-Y., Huber T., Lescar J., Luo D., Vasudevan S.G.
出版 2020

A single amino acid in nonstructural protein NS4B Confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis

由 Grant, D., Tan, G.K., Qing, M., Ng, J.K.W., Yip, A., Zou, G., Xie, X., Yuan, Z.Y., Schreiber, J., Schul, W., Shi, P.-Y., Alonso, S.
出版 2016

Partial genetic characterization of West Nile virus strains, New York State, 2000

由 Ebel, G.D, Dupuis II, A.P, Ngo, K, Nicholas, D, Kauffman, E, Jones, S.A, Young, D, Maffei, J, Shi, P.-Y, Bernard, K, Kramer, L.D
出版 2020

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

由 Lim, X.-N., Shan, C., Marzinek, J.K., Dong, H., Ng, T.S., Ooi, J.S.G., Fibriansah, G., Wang, J., Verma, C.S., Bond, P.J., Shi, P.-Y., Lok, S.-M.
出版 2021

2′-O methylation of internal adenosine by flavivirus NS5 methyltransferase

由 Dong, H., Chang, D.C., Hua, M.H.C., Lim, S.P., Chionh, Y.H., Hia, F., Lee, Y.H., Kukkaro, P., Lok, S.-M., Dedon, P.C., Shi, P.-Y.
出版 2016

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

由 Pompon J., Manuel M., Ng G.K., Wong B., Shan C., Manokaran G., Soto-Acosta R., Bradrick S.S., Ooi E.E., Missé D., Shi P.-Y., Garcia-Blanco M.A.
出版 2020

Understanding zika virus stability and developing a chimeric vaccine through functional analysis

由 Xie, X, Yang, Y, Muruato, A.E, Zou, J, Shan, C, Nunes, B.T.D, Medeiros, D.B.A, Vasconcelos, P.F.C, Weaver, S.C, Rossi, S.L, Shi, P.-Y
出版 2020

Characterization of a candidate tetravalent vaccine based on 2’-O-methyltransferase mutants

由 Züst R., Li S.-H., Xie X., Velumani S., Chng M., Toh Y.-X., Zou J., Dong H., Shan C., Pang J., Qin C.-F., Newell E.W., Shi P.-Y., Fink K.
出版 2019

A novel reporter system for neutralizing and enhancing antibody assay against dengue virus

由 Song, K.-Y, Zhao, H, Jiang, Z.-Y, Li, X.-F, Deng, Y.-Q, Jiang, T, Zhu, S.-Y, Shi, P.-Y, Zhang, B, Zhang, F.-C, Qin, E.-D, Qin, C.-F
出版 2020