First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid...

by Piha-Paul, Sarina A, Geva, Ravit, Tan, Tira J, Lim, Darren Wt, Hierro, Cinta, Doi, Toshikiko, Rahma, Osama, Lesokhin, Alexander, Luke, Jason John, Otero, Javier, Nardi, Lisa, Singh, Angad, Xyrafas, Alexandros, Chen, Xinhui, Mataraza, Jennifer, Bedard, Philippe L
Published 2022

Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

by Zhu, Guanhua, Guo, Yu A., Ho, Danliang, Poon, Polly, Poh, Zhong Wee, Wong, Pui Mun, Gan, Anna, Chang, Mei Mei, Kleftogiannis, Dimitrios, Lau, Yi Ting, Tay, Brenda, Lim, Wan Jun, Chua, Clarinda, Tan, Tira J., Koo, Si-Lin, Chong, Dawn Q., Yap, Yoon Sim, Tan, Iain, Ng, Sarah, Skanderup, Anders J.
Published 2022

Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cance...

by Kong, Say Li, Liu, Xingliang, Tan, Swee Jin, Tai, Joyce A, Phua, Ler Yee, Poh, Huay Mei, Yeo, Trifanny, Chua, Yong Wei, Haw, Yu Xuan, Ling, Wen Huan, Ng, Raymond Chee Hui, Tan, Tira J, Loh, Kiley Wei Jen, Tan, Daniel Shao-Weng, Ng, Quan Sing, Ang, Mei Kim, Toh, Chee Keong, Lee, Yi Fang, Lim, Chwee Teck, Lim, Tony Kiat Hon, Hillmer, Axel M, Yap, Yoon Sim, Lim, Wan-Teck
Published 2022

Multi-center evaluation of artificial intelligent imaging and clinical models for predicting neoadjuvant chemotherapy response in breast cancer

by Tan, Hong Qi, Ong, Hiok Hian, Kumaran, Arjunan Muthu, Tan, Tira J., Tan, Ryan Ying Cong, Lee, Ghislaine Su-Xin, Lim, Elaine Hsuen, Ng, Raymond, Yeo, Richard Ming Chert, Lim, Faye Lynette Tching Wei, Zhang, Zewen, Yang, Christina Shi Hui, Wong, Ru Xin, Ooi, Gideon Su Kai, Chee, Lester Hao Leong, Tan, Su Ming, Preetha, Madhukumar, Sim, Yirong, Tan, Veronique Kiak Mien, Yeong, Joe, Wong, Fuh Yong, Cai, Yiyu, Nei, Wen Long, JBCR, Ai3
Published 2022

Individualized Molecular Profiling for Allocation to Clinical Trials Singapore Study-An Asian Tertiary Cancer Center Experience

by Seet, Amanda OL, Tan, Aaron C, Tan, Tira J, Ng, Matthew CH, Tai, David WM, Lam, Justina YC, San Tan, Gek, Gogna, Apoorva, Too, Chow Wei, Tan, Bien Soo, Takano, Angela, Lim, Alvin, Lim, Tse Hui, Lim, Soon Thye, Dent, Rebecca Alexandra, Ang, Mei Kim, Yap, Yoon-Sim, Tan, Iain BH, Choo, Su Pin, Toh, Chee Keong, Lim, Elaine H, Farid, Mohamad, Skanderup, Anders Jacobsen, Iyer, N Gopalakrishna, Lim, Wan Teck, Tan, Eng Huat, Lim, Tony KH, Tan, Daniel SW
Published 2024

Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer

by Loo, Ser Yue, Toh, Li Ping, Xie, William Haowei, Pathak, Elina, Tan, Wilson, Ma, Siming, Lee, May Yin, Shatishwaran, S., Yeo, Joanna Zhen Zhen, Yuan, Ju, Ho, Yin Ying, Peh, Esther Kai Lay, Muniandy, Magendran, Torta, Federico, Chan, Jack, Tan, Tira J., Sim, Yirong, Tan, Veronique, Tan, Benita, Madhukumar, Preetha, Yong, Wei Sean, Ong, Kong Wee, Wong, Chow Yin, Tan, Puay Hoon, Yap, Yoon Sim, Deng, Lih-Wen, Dent, Rebecca, Foo, Roger, Wenk, Markus R., Lee, Soo Chin, Ho, Ying Swan, Lim, Elaine Hsuen, Tam, Wai Leong
Published 2022