Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance

由 Lee, Miyoung, Shorthouse, David, Mahen, Robert, Hall, Benjamin A., Venkitaraman, Ashok R.
出版 2022

Investigating peptide sequence variations for ‘double-click’ stapled p53 peptides

由 Lau, Yu Heng, de Andrade, Peterson, Sköld, Niklas, McKenzie, Grahame J., Venkitaraman, Ashok R., Verma, Chandra, Lane, David P., Spring, David R.
出版 2016

Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity

由 Wang, Yu-Hsiu, Ho, Teresa L. F., Hariharan, Anushya, Goh, Hui Chin, Wong, Yao Liang, Verkaik, Nicole S., Lee, May Yin, Tam, Wai Leong, van Gent, Dik C., Venkitaraman, Ashok R., Sheetz, Michael P., Lane, David P.
出版 2022

Functionalised staple linkages for modulating the cellular activity of stapled peptides

由 Lau, Yu Heng, de Andrade, Peterson, Quah, Soo-Tng, Rossmann, Maxim, Laraia, Luca, Sköld, Niklas, Sum, Tze Jing, Rowling, Pamela J. E., Joseph, Thomas L., Verma, Chandra, Hyvönen, Marko, Itzhaki, Laura S., Venkitaraman, Ashok R., Brown, Christopher J., Lane, David P., Spring, David R.
出版 2016

Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation

由 Kong, Li Ren, Ong, Richard Weijie, Tan, Tuan Zea, Salleh, Nur Afiqah Binte Mohamed, Thangavelu, Matan, Chan, Jane Vin, Koh, Lie Yong Judice, Periyasamy, Giridharan, Lau, Jieying Amelia, Le, Thi Bich Uyen, Wang, Lingzhi, Lee, Miyoung, Kannan, Srinivasaraghavan, Verma, Chandra S, Lim, Chwee Ming, Chng, Wee Joo, Lane, David P, Venkitaraman, Ashok, Hung, Huynh The, Cheok, Chit Fang, Goh, Boon Cher
出版 2020

Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities

由 Ho, Teresa Lai Fong, Lee, May Yin, Goh, Hui Chin, Ng, Germaine Yi Ning, Lee, Jane Jia Hui, Kannan, Srinivasaraghavan, Lim, Yan Ting, Zhao, Tianyun, Lim, Edwin Kok Hao, Phua, Cheryl Zi Jin, Lee, Yi Fei, Lim, Rebecca Yi Xuan, Ng, Perry Jun Hao, Yuan, Ju, Chan, Dedrick Kok Hong, Lieske, Bettina, Chong, Choon Seng, Lee, Kuok Chung, Lum, Jeffrey, Cheong, Wai Kit, Yeoh, Khay Guan, Tan, Ker Kan, Sobota, Radoslaw M, Verma, Chandra S, Lane, David P, Tam, Wai Leong, Venkitaraman, Ashok R
出版 2023

Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities

由 Ho, Teresa Lai Fong, Lee, May Yin, Goh, Hui Chin, Ng, Germaine Yi Ning, Lee, Jane Jia Hui, Kannan, Srinivasaraghavan, Lim, Yan Ting, Zhao, Tianyun, Lim, Edwin Kok Hao, Phua, Cheryl Zi Jin, Lee, Yi Fei, Lim, Rebecca Yi Xuan, Ng, Perry Jun Hao, Yuan, Ju, Chan, Dedrick Kok Hong, Lieske, Bettina, Chong, Choon Seng, Lee, Kuok Chung, Lum, Jeffrey, Cheong, Wai Kit, Yeoh, Khay Guan, Tan, Ker Kan, Sobota, Radoslaw M., Verma, Chandra Shekhar, Lane, David P., Tam, Wai Leong, Venkitaraman, Ashok R.
出版 2023