Conformational ordering of intrinsically disordered peptides for targeting translation initiation

by Brown, Christopher J., Verma, Chandra S., Lane, David P., Lama, Dilraj
Published 2022

Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides

by Li, Jianguo, Kannan, Srinivasaraghavan, Aronica, Pietro, Brown, Christopher J., Partridge, Anthony W., Verma, Chandra Shekhar
Published 2022

Improved eIF4E binding peptides by phage display guided design : plasticity of interacting surfaces yield collective effects

by Zhou, Weizhuang., Verma, Chandra Shekhar., Liu, Yun., Lane, David P., Brown, Christopher J., Tng, Quah Soo.
Published 2013

Rational optimization of conformational effects induced by hydrocarbon staples in peptides and their binding interfaces

by Lama, Dilraj, Lakshminarayanan, Rajamani, Lane, David P., Brown, Christopher J., Quah, Soo T., Verma, Chandra S., Beuerman, Roger W.
Published 2014

Water-Bridge Mediates Recognition of mRNA Cap in eIF4E

by Lama, Dilraj, Pradhan, Mohan R., Brown, Christopher J., Eapen, Rohan S., Joseph, Thomas L., Kwoh, Chee-Keong, Lane, David P., Verma, Chandra Shekhar
Published 2017

Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein

by Lama, Dilraj, Liberatore, Anne-Marie, Frosi, Yuri, Nakhle, Jessica, Tsomaia, Natia, Bashir, Tarig, Lane, David P., Brown, Christopher J., Verma, Chandra Shekhar, Auvin, Serge
Published 2019

Binding of translationally controlled tumour protein to the N-terminal domain of HDM2 is inhibited by Nutlin-3

by Funston, Garth., Goh, Walter., Wei, Siau Jia., Tng, Quah Soo., Tong, Loh Jiah., Verma, Chandra Shekhar., Ghadessy, Farid., Lane, David P., Brown, Christopher J.
Published 2013

Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2

by Chee, Sharon Min Qi, Wongsantichon, Jantana, Soo Tng, Quah, Robinson, Robert, Joseph, Thomas L., Verma, Chandra, Lane, David P., Brown, Christopher J., Ghadessy, Farid J.
Published 2014

Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays

by Brown, Christopher J., Ferrer, Fernando J., Yuen, Tsz Ying, Quah, Soo Tng, Chan, Boon Hong, Teo, Hsiang Ling, Nordlund, Pär, Lane, David P., Tan, Ban Xiong, Jansson, Anna Elisabet
Published 2015

Functionalised staple linkages for modulating the cellular activity of stapled peptides

by Lau, Yu Heng, de Andrade, Peterson, Quah, Soo-Tng, Rossmann, Maxim, Laraia, Luca, Sköld, Niklas, Sum, Tze Jing, Rowling, Pamela J. E., Joseph, Thomas L., Verma, Chandra, Hyvönen, Marko, Itzhaki, Laura S., Venkitaraman, Ashok R., Brown, Christopher J., Lane, David P., Spring, David R.
Published 2016

Future carbon emissions from global mangrove forest loss

by Adame, Maria F., Connolly, Rod M., Turschwell, Mischa P., Lovelock, Catherine E., Fatoyinbo, Temilola, Lagomasino, David, Goldberg, Liza A., Holdorf, Jordan, Friess, Daniel A., Sasmito, Sigit D., Sanderman, Jonathan, Sievers, Michael, Buelow, Christina, Kauffman, J. Boone, Bryan-Brown, Dale, Brown, Christopher J.
Published 2022

Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex

by Frosi, Yuri, Lin, Yen-Chu, Jiang, Shimin, Ramlan, Siti Radhiah, Hew, Kelly, Engman, Alf Henrik, Pillai, Anil, Yeung, Kit, Cheng, Yue Xiang, Cornvik, Tobias, Nordlund, Par, Goh, Megan, Lama, Dilraj, Gates, Zachary P., Verma, Chandra Shekhar, Thean, Dawn, Lane, David P., Asial, Ignacio, Brown, Christopher J.
Published 2023