The influences of substrates' physical properties on enzymatic PET hydrolysis: implications for PET hydrolase engineering

by Pasula, Rupali Reddy, Lim, Sierin, Ghadessy, Farid J., Sana, Barindra
Published 2022

Going native: Complete removal of protein purification affinity tags by simple modification of existing tags and proteases

by Goh, Hui Chin, Sobota, Radoslaw M., Ghadessy, Farid J., Nirantar, Saurabh
Published 2017

Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics

by Sun, Yue, Lau, Sze Yi, Lim, Zhi Wei, Chang, Shi Chieh, Ghadessy, Farid, Partridge, Anthony, Miserez, Ali
Published 2022

A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression

by Makhija, Harshyaa, Roy, Suki, Hoon, Shawn, Ghadessy, Farid John, Wong, Desmond, Jaiswal, Rahul, Campana, Dario, Dröge, Peter
Published 2019

In vitro selection of mutant HDM2 resistant to nutlin inhibition

by Wei, Siau Jia., Joseph, Thomas., Sim, Adelene Y. L., Yurlova, Larisa., Zolghadr, Kourosh., Lane, David., Verma, Chandra., Ghadessy, Farid.
Published 2014

Development and application of a transcriptional sensor for detection of heterologous acrylic acid production in E. coli

by Raghavan, Sarada S., Chee, Sharon, Li, Juntao, Poschmann, Jeremie, Nagarajan, Niranjan, Wei, Siau Jia, Verma, Chandra Shekhar, Ghadessy, Farid John
Published 2020

Engineered RebH Halogenase Variants Demonstrating a Specificity Switch from Tryptophan towards Novel Indole Compounds

by Sana, Barindra, Ho, Timothy, Kannan, Srinivasaraghavan, Ke, Ding, Li, Eunice H. Y., Seayad, Jayasree, Verma, Chandra S., Duong, Hung A., Ghadessy, Farid J.
Published 2022

Binding of translationally controlled tumour protein to the N-terminal domain of HDM2 is inhibited by Nutlin-3

by Funston, Garth., Goh, Walter., Wei, Siau Jia., Tng, Quah Soo., Tong, Loh Jiah., Verma, Chandra Shekhar., Ghadessy, Farid., Lane, David P., Brown, Christopher J.
Published 2013

Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket

by Siau, Jia Wei, Kannan, Srinivasaraghavan, Ouaray, Zohra, Kwoh, Chee Keong, Ghadessy, Farid, Pradhan, Mohan Rajan, Nguyen, Minh N., Lane, David P., Verma, Chandra Shekhar
Published 2019

Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2

by Chee, Sharon Min Qi, Wongsantichon, Jantana, Soo Tng, Quah, Robinson, Robert, Joseph, Thomas L., Verma, Chandra, Lane, David P., Brown, Christopher J., Ghadessy, Farid J.
Published 2014

Conservative site-specific and single-copy transgenesis in human LINE-1 elements

by Vijaya Chandra, Shree Harsha, Makhija, Harshyaa, Peter, Sabrina, Myint Wai, Cho Mar, Li, Jinming, Zhu, Jindong, Ren, Zhonglu, D'Alcontres, Martina Stagno, Siau, Jia Wei, Chee, Sharon, Ghadessy, Farid John, Dröge, Peter
Published 2018

The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans

by Venkatesh, Byrappa, Lane, David P., Coffill, Cynthia R., Lee, Alison P., Siau, Jia Wei, Chee, Sharon M., Joseph, Thomas L., Tan, Yaw Sing, Madhumalar, Arumugam, Tay, Boon-Hui, Brenner, Sydney, Verma, Chandra Shekhar, Ghadessy, Farid J.
Published 2016