OPTIMIZATION OF FORMULA AND MANUFACTURING PROCESS USING THE DESIGN OF EXPERIMENT METHOD TO IMPROVE THE PRODUCT’S STABILITY AND QUALITY OF FACE WASH X

• Main Author: Adi Atmaja, Himawan
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/66277
• Institution: Institut Teknologi Bandung

This study aims to solve the problem in PT. XYZ due to consumer’s complaints in product Face Wash X which has phase separation and the consistency is too runny. The study was conducted by analyzing potential sources of problems using evaluation notes during product development, Ishikawa-Fishbone Diagram, and Failure Mode Effect Analysis (FMEA) on the stability and consistency response of the product that was used as a Critical Quality Attribute (CQA), namely the pH value (Y1), viscosity (Y2), & the difference in conductivity (Y3) between the products before and after the accelerated stability using the heating-cooling method. Factors that are considered to affect the CQA of the product are the concentration of poly-ol (X1), fatty alcohol concentration (X2), surfactant concentration (X3), and process termination temperature (X4) were optimized using the Design of Experiment (DOE)-Box Bhenken and resulting the factors that theoretically will give optimum responses according to the product CQA, X1 at 21.72%, X2 at 3.93%, X3 at 5.12%, and X4 at 50°C. Design space is created by overlaying plots. Further analysis was carried out by comparing the theoretical response with the actual response. From the experimental results, the error in all responses is smaller than the degree of confidence 5.00%. The accelerated stability evaluation concluded that the optimized product was stable with no separation found through visual observations or changes in microscopic structure observations, and no statistically significant shift in peak temperature thermal values. Based on the results, the results of the optimization of the formula and manufacturing process of face wash X using the Design of Experiment (DOE) method can be applied to PT. XYZ.