DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD OF N-NITROSODIMETHYLAMINE (NDMA), N-NITROSODIETHYLAMINE (NDEA), N-NITROSOMETHYLAMINOBUTYRIC ACID (NMBA), N-NITROSOETYLISOPROPILAMINE (NEIPA), AND N-NITROSODIISOPROPILAMINE (NDIPA) IMPURITY IN CANDESARTAN CILEXETIL TABLET

DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD OF N-NITROSODIMETHYLAMINE (NDMA), N-NITROSODIETHYLAMINE (NDEA), N-NITROSOMETHYLAMINOBUTYRIC ACID (NMBA), N-NITROSOETYLISOPROPILAMINE (NEIPA), AND N-NITROSODIISOPROPILAMINE (NDIPA) IMPURITY IN CANDESARTAN CILEXETIL TABLET

Nitrosamines are chemical compounds classified as probable human carcinogens based on animal studies. These angiostensin-receptor blocker medicines have a specific ring structure (tetrazole) whose synthesis could potentially lead to the formation of nitrosamine impurities. An ultra-performance li...

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Bibliographic Details
Main Author:	Firmana, Triziya
Format:	Theses
Language:	Indonesia
Online Access:	https://digilib.itb.ac.id/gdl/view/69044
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Institut Teknologi Bandung
Language:	Indonesia

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