Structure-based discovery of small molecule APC-Asef interaction inhibitors: In silico approaches and molecular dynamics simulations

Colorectal cancer, which is considered one of the leading causes of mortality worldwide, develops through the formation of benign polyps on the inner colon or rectum wall. Truncations in adenomatous polyposis coli (APC) gene lead to the spread of the disease in the entire colon region when combined...

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Main Authors: Jadav, Surender Singh, Macalino, Stephani Joy Y., Alluri, Ramesh
Format: text
Published: Animo Repository 2020
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/1399
https://animorepository.dlsu.edu.ph/context/faculty_research/article/2398/type/native/viewcontent/s00894_020_04467_5.html
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Institution: De La Salle University

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