Expression levels of microRNA machinery components Drosha, dicer and DGCR8 in human (AGS, HepG2, and KEYSE-30) cancer cell lines

• Main Authors: Jafari, Naser, Peeri Dogaheh, Hadi, Bohlooli, Shahab, Oyong, Glenn G., Shirzad, Zohreh, Alibeiki, Fatemeh, Hosseini Asl, Saeid, Jalal Zargar, Seyed
• Format: text
• Published: Animo Repository 2013
• Subjects: MicroRNA; Cancer cells—Growth; RNA-protein interactions; Biology
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/2450
• Institution: De La Salle University

MicroRNAs (miRNAs) have recently been shown to play fundamental roles in diverse cellular processes and linked to variety of cancers. Dicer and Drosha are two major enzymes in the miRNA maturation process. DGCR8 is the assistant of Drosha in the microprocessor complex. In this study, we evaluated th...