Direct and stereospecific interaction of amphidinol 3 with sterol in lipid bilayers
Amphidinol 3 (AM3), a polyhydroxy-polyene metabolite from the dinoflagellate Amphidinium klebsii, possesses potent antifungal activity. Although AM3 permeabilizes phospholipid membranes only in the presence of sterol, the detailed molecular basis by which AM3 recognizes sterols in membranes remains...
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| Main Authors: | , , , |
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| Format: | text |
| Published: |
Animo Repository
2014
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| Subjects: | |
| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/5119 |
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| Institution: | De La Salle University |