Direct and stereospecific interaction of amphidinol 3 with sterol in lipid bilayers

Amphidinol 3 (AM3), a polyhydroxy-polyene metabolite from the dinoflagellate Amphidinium klebsii, possesses potent antifungal activity. Although AM3 permeabilizes phospholipid membranes only in the presence of sterol, the detailed molecular basis by which AM3 recognizes sterols in membranes remains...

Full description

Saved in:
Bibliographic Details
Main Authors: Espiritu, Rafael Atillo, Matsumori, Nobuaki, Tsuda, Masashi, Murata, Michio
Format: text
Published: Animo Repository 2014
Subjects:
Online Access:https://animorepository.dlsu.edu.ph/faculty_research/5119
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: De La Salle University

Similar Items