Assessing the binding affinity of a selected class of DPP4 inhibitors using chemical descriptor-based multiple linear regression
The activity of a selected class of DPP4 inhibitors was preliminary assessed using chemical descriptors derived AM1 optimized geometries. Using multiple linear regression model, it was found that ΔE0 , LUMO energy, area, molecular weight and ΔH0 are the significant descriptors that can adequately as...
Saved in:
Main Authors: | , , , |
---|---|
Format: | text |
Published: |
Animo Repository
2011
|
Subjects: | |
Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/6604 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | De La Salle University |