Assessing the binding affinity of a selected class of DPP4 inhibitors using chemical descriptor-based multiple linear regression
The activity of a selected class of DPP4 inhibitors was preliminary assessed using chemical descriptors derived AM1 optimized geometries. Using multiple linear regression model, it was found that ΔE0 , LUMO energy, area, molecular weight and ΔH0 are the significant descriptors that can adequately as...
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| Main Authors: | , , , |
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| Format: | text |
| Published: |
Animo Repository
2011
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| Subjects: | |
| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/6604 |
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| Institution: | De La Salle University |