HMGA2 inhibits apoptosis through interaction with ATR-CHK1 signaling complex in human cancer cells

The non-histone chromatin binding protein high mobility group AT-hook 2 (HMGA2) is expressed in stem cells and many cancer cells, including tumor initiating cells, but not translated in normal human somatic cells. The presence of HMGA2 is correlated with advanced neoplastic disease and poor prognosi...

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Bibliographic Details
Main Authors: Suchitra, Natarajan, Sabine, Hombach-Klonisch, Peter, Dröge, Thomas, Klonisch
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/101351
http://hdl.handle.net/10220/19411
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593150/
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Institution: Nanyang Technological University
Language: English

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