Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines

Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines

A chiral palladacycle-promoted enantioselective asymmetric hydrophosphination of substituted methylidenemalonate esters using diphenylphosphine that provides direct access to chiral tertiary phosphines is reported. Screening of three easily accessible C,N and C,P palladacycles as catalysts for this...

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Main Authors: Pullarkat, Sumod A., Xu, Chang, Gan, Kennard Jun Hao, Hennersdorf, Felix, Li, Yongxin, Leung, Pak-Hing
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/101494
http://hdl.handle.net/10220/13698
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1014942020-03-07T12:34:50Z Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines Pullarkat, Sumod A. Xu, Chang Gan, Kennard Jun Hao Hennersdorf, Felix Li, Yongxin Leung, Pak-Hing School of Physical and Mathematical Sciences A chiral palladacycle-promoted enantioselective asymmetric hydrophosphination of substituted methylidenemalonate esters using diphenylphosphine that provides direct access to chiral tertiary phosphines is reported. Screening of three easily accessible C,N and C,P palladacycles as catalysts for this synthetic scenario provided insights into critical factors in catalyst design that influence the activation and stereochemistry in Pd(II)-catalyzed asymmetric P–H addition reactions involving such activated substrates. 2013-09-25T07:52:32Z 2019-12-06T20:39:15Z 2013-09-25T07:52:32Z 2019-12-06T20:39:15Z 2012 2012 Journal Article Xu, C., Gan, K. J. H., Hennersdorf, F., Li, Y., Pullarkat, S. A., & Leung, P.-H. (2012). Chiral Phosphapalladacycles as Efficient Catalysts for the Asymmetric Hydrophosphination of Substituted Methylidenemalonate Esters: Direct Access to Functionalized Tertiary Chiral Phosphines. Organometallics, 31(8), 3022–3026. https://hdl.handle.net/10356/101494 http://hdl.handle.net/10220/13698 10.1021/om201115n en Organometallics
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description A chiral palladacycle-promoted enantioselective asymmetric hydrophosphination of substituted methylidenemalonate esters using diphenylphosphine that provides direct access to chiral tertiary phosphines is reported. Screening of three easily accessible C,N and C,P palladacycles as catalysts for this synthetic scenario provided insights into critical factors in catalyst design that influence the activation and stereochemistry in Pd(II)-catalyzed asymmetric P–H addition reactions involving such activated substrates.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Pullarkat, Sumod A.
Xu, Chang
Gan, Kennard Jun Hao
Hennersdorf, Felix
Li, Yongxin
Leung, Pak-Hing
format Article
author Pullarkat, Sumod A.
Xu, Chang
Gan, Kennard Jun Hao
Hennersdorf, Felix
Li, Yongxin
Leung, Pak-Hing
spellingShingle Pullarkat, Sumod A.
Xu, Chang
Gan, Kennard Jun Hao
Hennersdorf, Felix
Li, Yongxin
Leung, Pak-Hing
Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
author_sort Pullarkat, Sumod A.
title Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
title_short Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
title_full Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
title_fullStr Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
title_full_unstemmed Chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
title_sort chiral phosphapalladacycles as efficient catalysts for the asymmetric hydrophosphination of substituted methylidenemalonate esters : direct access to functionalized tertiary chiral phosphines
publishDate 2013
url https://hdl.handle.net/10356/101494
http://hdl.handle.net/10220/13698
_version_ 1681042593486471168

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