Identification of LasR ligands through a virtual screening approach

• المؤلفون الرئيسيون: Skovstrup, Søren, Le Quement, Sebastian Thordal, Hansen, Thomas, Jakobsen, Tim Holm, Harmsen, Morten, Tolker-Nielsen, Tim, Nielsen, Thomas E., Givskov, Michael, Taboureau, Olivier
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Medicine::Biomedical engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/101701; http://hdl.handle.net/10220/19785
• المؤسسة: Nanyang Technological University

With the widespread occurrence of bacterial resistance to antibiotics, the development of new strategies beyond conventional treatments is a pursuit taken by public health institutions worldwide. LasR, a transcription factor that controls quorum sensing in Pseudomonas aeruginosa, has emerged as an a...