Identification of LasR ligands through a virtual screening approach
With the widespread occurrence of bacterial resistance to antibiotics, the development of new strategies beyond conventional treatments is a pursuit taken by public health institutions worldwide. LasR, a transcription factor that controls quorum sensing in Pseudomonas aeruginosa, has emerged as an a...
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Main Authors: | Skovstrup, Søren, Le Quement, Sebastian Thordal, Hansen, Thomas, Jakobsen, Tim Holm, Harmsen, Morten, Tolker-Nielsen, Tim, Nielsen, Thomas E., Givskov, Michael, Taboureau, Olivier |
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Format: | Article |
Language: | English |
Published: |
2014
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/101701 http://hdl.handle.net/10220/19785 |
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Institution: | Nanyang Technological University |
Language: | English |
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