Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC3
Phen-DC3 is a highly promising compound that specifically targets G-quadruplexes, with potent biological effects observed in vivo. We used NMR spectroscopy to solve the structure of the complex formed between Phen-DC3 and an intramolecular G-quadruplex derived from the c-myc promoter. Structural inf...
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| Main Authors: | , , , , |
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| 格式: | Article |
| 語言: | English |
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2014
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| 在線閱讀: | https://hdl.handle.net/10356/102946 http://hdl.handle.net/10220/19192 |
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