Mapping the interactions between the NS4B and NS3 proteins of dengue virus

• المؤلفون الرئيسيون: Zou, Jing, Lee, Le Tian, Wang, Qing Yin, Xie, Xuping, Lu, Siyan, Yau, Yin Hoe, Yuan, Zhiming, Geifman Shochat, Susana, Kang, Congbao, Lescar, Julien, Shi, Pei-Yong
• مؤلفون آخرون: Dermody, T. S.
• التنسيق: مقال
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Microbiology::Virology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/103132; http://hdl.handle.net/10220/25837

Flavivirus RNA synthesis is mediated by a multiprotein complex associated with the endoplasmic reticulum membrane, named the replication complex (RC). Within the flavivirus RC, NS4B, an integral membrane protein with a role in virulence and regulation of the innate immune response, binds to the NS3...