Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays

Previous publications on stapled peptide inhibitors against Mdm2/Mdm4-p53 interactions have established that this new class of drugs have the potential to be easily optimised to attain high binding affinity and specificity, but the mechanisms controlling their cellular uptake and target engagement r...

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Bibliographic Details
Main Authors: Brown, Christopher J., Ferrer, Fernando J., Yuen, Tsz Ying, Quah, Soo Tng, Chan, Boon Hong, Teo, Hsiang Ling, Nordlund, Pär, Lane, David P., Tan, Ban Xiong, Jansson, Anna Elisabet
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/103179
http://hdl.handle.net/10220/38721
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Institution: Nanyang Technological University
Language: English
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