Discovery of Dengue Virus NS4B Inhibitors
The four serotypes of dengue virus (DENV-1 to -4) represent the most prevalent mosquito-borne viral pathogens in humans. No clinically approved vaccine or antiviral is currently available for DENV. Here we report a spiropyrazolopyridone compound that potently inhibits DENV both in vitro and in vivo....
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2015
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Online Access: | https://hdl.handle.net/10356/103770 http://hdl.handle.net/10220/38794 |
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Institution: | Nanyang Technological University |
Language: | English |