Precise control of movement kinematics by optogenetic inhibition of purkinje cell activity

Purkinje cells (PCs) of the cerebellar cortex are necessary for controlling movement with precision, but a mechanistic explanation of how the activity of these inhibitory neurons regulates motor output is still lacking.Weused an optogenetic approach in awake mice to show for the first time that tr...

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Bibliographic Details
Main Authors: Heiney, Shane A., Kim, Jinsook, Augustine, George J., Medina, Javier F.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103883
http://hdl.handle.net/10220/19334
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Institution: Nanyang Technological University
Language: English

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