Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector

Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector

Hematopoietic Stem Cell (HSC) targeted gene transfer is an attractive treatment option for a number of hematopoietic disorders caused by single gene defects. However, extensive methylation of promoter sequences results in silencing of therapeutic gene expression. The choice of an appropriate promote...

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書目詳細資料
Main Authors:	Dighe, Niraja, Khoury, Maroun, Mattar, Citra, Chong, Mark, Choolani, Mahesh, Chen, Jianzhu, Antoniou, Michael N., Chan, Jerry Kok Yen
其他作者:	Santiago, Mario L.
格式:	Article
語言:	English
出版:	2014
主題:	DRNTU::Engineering::Chemical engineering::Biochemical engineering
在線閱讀:	https://hdl.handle.net/10356/104904 http://hdl.handle.net/10220/20409
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	Nanyang Technological University
語言:	English

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