1-(2′-Anilinyl)prop-2-yn-1-ol rearrangement for oxindole synthesis
A synthetic method that relies on NIS (N-iodosuccinimide)-mediated cycloisomerization reactions of 1-(2′-anilinyl)prop-2-yn-1-ols to gem-3-(diiodomethyl)indolin-2-ones and 2-(iodomethylene)indolin-3-ones has been developed. The reactions were shown to be chemoselective, with secondary and tertiary a...
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Main Authors: | Kothandaraman, Prasath, Koh, Bing Qin, Limpanuparb, Taweetham, Hirao, Hajime, Chan, Philip Wai Hong |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Online Access: | https://hdl.handle.net/10356/105286 http://hdl.handle.net/10220/16575 http://dx.doi.org/10.1002/chem.201202606 |
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Institution: | Nanyang Technological University |
Language: | English |
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