Silver triflate catalyzed cyclopropyl carbinol rearrangement for benzo[b]oxepine and 2H-chromene synthesis

• Main Authors: Chan, Philip Wai Hong, Teo, Wan Teng, Koh, Shaun Wei Yong, Lee, Bo Ra, Ayers, Benjamin James, Ma, Dik-Lung, Leung, Chung-Hang
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2015
• 主題: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• 在線閱讀: https://hdl.handle.net/10356/105560; http://hdl.handle.net/10220/25972; http://dx.doi.org/10.1002/ejoc.201500374
• 機構: Nanyang Technological University

An efficient AgOTf-catalyzed (TfO = trifluoromethanesulfonate) cyclopropyl carbinol rearrangement for the synthesis of benzo[b]oxepines and 2H-chromenes is reported by starting from 2-[cyclopropyl(hydroxy)methyl]phenols. The reactions proved to be general in scope and furnished a range of the corres...