Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites

Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites

Heterochromatin-dependent gene silencing is central to the adaptation and survival of Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during blood infection in humans. By assessing genome-wide heterochromatin protein 1 (HP1) occupancy, we present a comprehensive an...

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Bibliographic Details
Main Authors: Fraschka, Sabine A., Filarsky, Michael, Hoo, Regina, Niederwieser, Igor, Yam, Xue Yan, Mohring, Franziska, Huang, Ximei, Christensen, Peter R., Nosten, Francois, Bozdech, Zbynek, Russell, Bruce, Moon, Robert W., Marti, Matthias, Bártfai, Richárd, Voss, Till S., Brancucci, Nicolas M. B., Mushunje, Annals Tatenda, Preiser, Peter Rainer
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Plasmodium
Malaria
Science::Biological sciences
Online Access:https://hdl.handle.net/10356/106386
http://hdl.handle.net/10220/49617
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/106386
http://hdl.handle.net/10220/49617

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