Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites
Heterochromatin-dependent gene silencing is central to the adaptation and survival of Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during blood infection in humans. By assessing genome-wide heterochromatin protein 1 (HP1) occupancy, we present a comprehensive an...
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Main Authors: | Fraschka, Sabine A., Filarsky, Michael, Hoo, Regina, Niederwieser, Igor, Yam, Xue Yan, Mohring, Franziska, Huang, Ximei, Christensen, Peter R., Nosten, Francois, Bozdech, Zbynek, Russell, Bruce, Moon, Robert W., Marti, Matthias, Bártfai, Richárd, Voss, Till S., Brancucci, Nicolas M. B., Mushunje, Annals Tatenda, Preiser, Peter Rainer |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/106386 http://hdl.handle.net/10220/49617 |
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Institution: | Nanyang Technological University |
Language: | English |
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