Palladium-catalyzed asymmetric reductive heck reaction of aryl halides

• Main Authors: Hirao, Hajime, Zhou, Jianrong Steve, Yue, Guizhou, Lei, Kaining
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Physics
• Online Access: https://hdl.handle.net/10356/107339; http://hdl.handle.net/10220/25531; http://dx.doi.org/10.1002/anie.201501712
• Institution: Nanyang Technological University

Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen-bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways.