A dual-function antibiotic-transporter conjugate exhibits superior activity in sterilizing MRSA biofilms and killing persister cells
New strategies are urgently needed to target MRSA, a major global health problem and the leading cause of mortality from antibiotic-resistant infections in many countries. Here, we report a general approach to this problem exemplified by the design and synthesis of a vancomycin-d-octaarginine conjug...
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Main Authors: | Antonoplis, Alexandra, Zang, Xiaoyu, Huttner, Melanie A., Chong, Kelvin Kian Long, Lee, Yu B., Co, Julia Y., Amieva, Manuel R., Kline, Kimberly A., Wender, Paul A., Cegelski, Lynette |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/137198 |
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Institution: | Nanyang Technological University |
Language: | English |
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