Ytterbium-catalyzed hydroboration of aldehydes and ketones
The well-defined heavy rare-earth ytterbium iodide complex 1 (L2YbI) has been successfully employed as an efficient catalyst for the hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) at room temperature. The protocol requires low catalyst loadings (0.1-0.5 mol %) and...
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sg-ntu-dr.10356-1376322020-04-07T03:29:45Z Ytterbium-catalyzed hydroboration of aldehydes and ketones Wang, Weifan Shen, Xingchao Zhao, Fengyi Jiang, Huan Yao, Weiwei Pullarkat, Sumod A. Xu, Li Ma, Mengtao School of Physical and Mathematical Sciences Science::Chemistry Ytterbium Ketones The well-defined heavy rare-earth ytterbium iodide complex 1 (L2YbI) has been successfully employed as an efficient catalyst for the hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) at room temperature. The protocol requires low catalyst loadings (0.1-0.5 mol %) and proceeds rapidly (>99% conversion in <10 min). Additionally, catalyst 1 shows a good functional group tolerance even toward the hydroxyl and amino moieties and displays chemoselective hydroboration of aldehydes over ketones under mild conditions. 2020-04-07T03:29:45Z 2020-04-07T03:29:45Z 2018 Journal Article Wang, W., Shen, X., Zhao, F., Jiang, H., Yao, W., Pullarkat, S. A., . . ., Ma, M. (2018). Ytterbium-catalyzed hydroboration of aldehydes and ketones. Journal of organic chemistry, 83(1), 69-74. doi:10.1021/acs.joc.7b02076 0022-3263 https://hdl.handle.net/10356/137632 10.1021/acs.joc.7b02076 29181979 2-s2.0-85037559643 1 83 69 74 en Journal of organic chemistry © 2017 American Chemical Society. All rights reserved. |
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Science::Chemistry Ytterbium Ketones |
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Science::Chemistry Ytterbium Ketones Wang, Weifan Shen, Xingchao Zhao, Fengyi Jiang, Huan Yao, Weiwei Pullarkat, Sumod A. Xu, Li Ma, Mengtao Ytterbium-catalyzed hydroboration of aldehydes and ketones |
| description |
The well-defined heavy rare-earth ytterbium iodide complex 1 (L2YbI) has been successfully employed as an efficient catalyst for the hydroboration of a wide range of aldehydes and ketones with pinacolborane (HBpin) at room temperature. The protocol requires low catalyst loadings (0.1-0.5 mol %) and proceeds rapidly (>99% conversion in <10 min). Additionally, catalyst 1 shows a good functional group tolerance even toward the hydroxyl and amino moieties and displays chemoselective hydroboration of aldehydes over ketones under mild conditions. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Wang, Weifan Shen, Xingchao Zhao, Fengyi Jiang, Huan Yao, Weiwei Pullarkat, Sumod A. Xu, Li Ma, Mengtao |
| format |
Article |
| author |
Wang, Weifan Shen, Xingchao Zhao, Fengyi Jiang, Huan Yao, Weiwei Pullarkat, Sumod A. Xu, Li Ma, Mengtao |
| author_sort |
Wang, Weifan |
| title |
Ytterbium-catalyzed hydroboration of aldehydes and ketones |
| title_short |
Ytterbium-catalyzed hydroboration of aldehydes and ketones |
| title_full |
Ytterbium-catalyzed hydroboration of aldehydes and ketones |
| title_fullStr |
Ytterbium-catalyzed hydroboration of aldehydes and ketones |
| title_full_unstemmed |
Ytterbium-catalyzed hydroboration of aldehydes and ketones |
| title_sort |
ytterbium-catalyzed hydroboration of aldehydes and ketones |
| publishDate |
2020 |
| url |
https://hdl.handle.net/10356/137632 |
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1681057395692797952 |