Macrolide synthesis through intramolecular oxidative cross‐coupling of alkenes

A RhIII‐catalyzed intramolecular oxidative cross‐coupling between double bonds for the synthesis of macrolides is described. Under the optimized reaction conditions, macrocycles containing a diene moiety can be formed in reasonable yields and with excellent chemo‐ and stereoselectivity. This method...

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Bibliographic Details
Main Authors: Jiang, Bing, Zhao, Meng, Li, Shu-Sen, Xu, Yun-He, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/137723
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Institution: Nanyang Technological University
Language: English