NHC-catalyzed chemoselective reactions of enals and aminobenzaldehydes for access to chiral dihydroquinolines

An N-heterocyclic carbene (NHC)-catalyzed reaction between α-bromoenals and 2-aminoaldehydes has been developed. Key steps include chemoselective reaction of the NHC catalyst with one of the aldehyde substrates (the bromoenal) to eventually generate an α,β-unsaturated acylazolium intermediate. Addit...

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Bibliographic Details
Main Authors: Wu, Shuquan, Liu, Changyi, Luo, Guoyong, Jin, Zhichao, Zheng, Pengcheng, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/137827
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Institution: Nanyang Technological University
Language: English
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