Digital karyotyping of cancer cell lines from NGS data
Human immortalized and transformed cell lines are the workhorse of cancer research. They are widely used to study cancer biology and to test and screen anti-cancer compounds in order to improve the efficacy of cancer treatment. Detection of DNA copy number alterations (CNAs) is critical to understan...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/138176 |
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| Institution: | Nanyang Technological University |
| Language: | English |