Palladium-catalyzed regioselective olefination of O-acetyl cyanohydrins

• المؤلفون الرئيسيون: Liang, Qiu-Ju, Jiang, Bing, Xu, Yun-He, Loh, Teck-Peng
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Chemistry; Chemical Reactions; Organic Compounds
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/139183
• المؤسسة: Nanyang Technological University

A practical palladium-catalyzed ortho-olefination of O-acetyl cyanohydrins assisted by synergetic directing groups has been developed. Thus, a range of olefinated O-acetyl cyanohydrins were synthesized in moderate to good yields. The reaction occurs efficiently with high regioselectivity and with a...