In vivo visualization of β-cells by targeting of GPR44

In vivo visualization of β-cells by targeting of GPR44

GPR44 expression has recently been described as highly β-cell selective in the human pancreas and constitutes a tentative surrogate imaging biomarker in diabetes. A radiolabeled small-molecule GPR44 antagonist, [11C]AZ12204657, was evaluated for visualization of β-cells in pigs and nonhuman primates...

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Bibliographic Details
Main Authors: Eriksson, Olof, Johnström, Peter, Cselenyi, Zsolt, Jahan, Mahabuba, Selvaraju, Ram K., Jensen-Waern, Marianne, Takano, Akihiro, Winzell, Maria Sörhede, Halldin, Christer, Skrtic, Stanko, Korsgren, Olle
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2020
Subjects:
Science::Medicine
In Vivo
GPR44
Online Access:https://hdl.handle.net/10356/142005
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/142005

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