In vivo visualization of β-cells by targeting of GPR44
GPR44 expression has recently been described as highly β-cell selective in the human pancreas and constitutes a tentative surrogate imaging biomarker in diabetes. A radiolabeled small-molecule GPR44 antagonist, [11C]AZ12204657, was evaluated for visualization of β-cells in pigs and nonhuman primates...
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Main Authors: | Eriksson, Olof, Johnström, Peter, Cselenyi, Zsolt, Jahan, Mahabuba, Selvaraju, Ram K., Jensen-Waern, Marianne, Takano, Akihiro, Winzell, Maria Sörhede, Halldin, Christer, Skrtic, Stanko, Korsgren, Olle |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/142005 |
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Institution: | Nanyang Technological University |
Language: | English |
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