Complement activation in vitro and reactogenicity of low-molecular weight dextran-coated SPIONs in the pig CARPA model : correlation with physicochemical features and clinical information

Complement activation in vitro and reactogenicity of low-molecular weight dextran-coated SPIONs in the pig CARPA model : correlation with physicochemical features and clinical information

The unique magnetic properties of superparamagnetic iron oxide nanoparticles (SPIONs) have led to their increasing use in drug delivery and imaging applications. Some polymer-coated SPIONs, however, share with many other nanoparticles the potential of causing hypersensitivity reactions (HSRs) known...

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Bibliographic Details
Main Authors: Fülöp, Tamás, Nemes, Réka, Mészáros, Tamás, Urbanics, Rudolf, Kok, Robbert Jan, Jackman, Joshua A., Cho, Nam-Joon, Storm, Gert, Szebeni, János
Other Authors: School of Materials Science and Engineering
Format: Article
Language:English
Published: 2020
Subjects:
Engineering::Materials
Complement
Hypersensitivity Reactions
Online Access:https://hdl.handle.net/10356/142114
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/142114

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