Complement activation in vitro and reactogenicity of low-molecular weight dextran-coated SPIONs in the pig CARPA model : correlation with physicochemical features and clinical information
The unique magnetic properties of superparamagnetic iron oxide nanoparticles (SPIONs) have led to their increasing use in drug delivery and imaging applications. Some polymer-coated SPIONs, however, share with many other nanoparticles the potential of causing hypersensitivity reactions (HSRs) known...
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Main Authors: | Fülöp, Tamás, Nemes, Réka, Mészáros, Tamás, Urbanics, Rudolf, Kok, Robbert Jan, Jackman, Joshua A., Cho, Nam-Joon, Storm, Gert, Szebeni, János |
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Other Authors: | School of Materials Science and Engineering |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/142114 |
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Institution: | Nanyang Technological University |
Language: | English |
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