Cobalt-catalyzed intermolecular [2+2] cycloaddition between alkynes and allenes

• Main Authors: Ding, Wei, Yoshikai, Naohiko
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Alkynes; Allenes
• Online Access: https://hdl.handle.net/10356/143608
• Institution: Nanyang Technological University

An intermolecular [2+2] cycloaddition reaction between an alkyne and an allene is reported. In the presence of a cobalt(I)/diphosphine catalyst, a near equimolar mixture of the alkyne and allene is converted into a 3-alkylidenecyclobutene derivative in good yield with high regioselectivity. The reac...