Iron-catalyzed ortho C−H arylation and methylation of pivalophenone N−H imines

• Main Authors: Xu, Wengang, Yoshikai, Naohiko
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Arylation; C−H Activation
• Online Access: https://hdl.handle.net/10356/143930
• Institution: Nanyang Technological University

Iron‐catalyzed ortho C−H arylation and methylation reactions of pivalophenone N−H imines are reported. The pivaloyl N−H imine proved an excellent directing group for the arylation with diarylzinc reagents in the presence of an iron‐diphosphine catalyst and 2,3‐dichlorobutane at room temperature. A s...